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ZM-447439

Synonyms

SourcesNames Used
GDSC1000ZM-447439
GRAYZM447439
PharmacoGx ZM-447439

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5
Inchikey: OGNYUTNQZVRGMN-UHFFFAOYSA-N
Pubchem: 9914412

Annotated Targets

AURKA, AURKB

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZM-447439


Feature TypeStandardized
Nominal ANOVA
mRNA SPAG4 GDSC1000 pan-cancer AAC -0.098 0.009
mRNA RNF121 GDSC1000 pan-cancer AAC -0.095 0.009
mRNA C19orf43 GDSC1000 pan-cancer AAC 0.098 0.009
mRNA GLOD4 GDSC1000 pan-cancer AAC 0.096 0.009
mRNA TCF7L2 GDSC1000 pan-cancer AAC 0.11 0.009
mRNA GNAI3 GDSC1000 pan-cancer AAC 0.097 0.009
mRNA EMC2 GDSC1000 pan-cancer AAC -0.096 0.009
mRNA TCEAL1 GDSC1000 pan-cancer AAC -0.11 0.009
mRNA ARIH2 GDSC1000 pan-cancer AAC 0.099 0.009
mRNA PPIL4 GDSC1000 pan-cancer AAC 0.093 0.009
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