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ZM-447439

Synonyms

SourcesNames Used
GDSC1000ZM-447439
GRAYZM447439
PharmacoGx ZM-447439

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5
Inchikey: OGNYUTNQZVRGMN-UHFFFAOYSA-N
Pubchem: 9914412

Annotated Targets

AURKA, AURKB

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZM-447439


Feature TypeStandardized
Nominal ANOVA
mRNA NEURL2 GDSC1000 pan-cancer AAC -0.092 0.01
mRNA LHFPL2 GDSC1000 pan-cancer AAC -0.1 0.01
mRNA GAS7 GDSC1000 pan-cancer AAC 0.12 0.01
mRNA XPO1 GDSC1000 pan-cancer AAC 0.093 0.01
mRNA TARBP1 GDSC1000 pan-cancer AAC 0.094 0.01
mRNA PLEKHG2 GDSC1000 pan-cancer AAC 0.096 0.01
mRNA KCNAB3 GDSC1000 pan-cancer AAC 0.1 0.01
mRNA CBLN2 GDSC1000 pan-cancer AAC -0.091 0.01
mRNA DUSP10 GDSC1000 pan-cancer AAC -0.099 0.01
mRNA GMEB1 GDSC1000 pan-cancer AAC 0.1 0.01
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