1. Home/
  2. Compounds/
  3. GDC-0449

GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA MAPK8 GDSC1000 pan-cancer AAC 0.13 0.0005
mRNA COX6C GDSC1000 pan-cancer AAC -0.13 0.0005
mRNA CEP162 GDSC1000 pan-cancer AAC 0.13 0.0005
mRNA SEC13 GDSC1000 pan-cancer AAC -0.13 0.0005
mRNA MXD3 GDSC1000 pan-cancer AAC -0.13 0.0005
mRNA CCT6A GDSC1000 pan-cancer AAC 0.12 0.0006
mRNA PSAT1 GDSC1000 pan-cancer AAC 0.12 0.0006
mRNA GLRA2 GDSC1000 pan-cancer AAC 0.12 0.0006
mRNA CARD8 FIMM pan-cancer AAC 0.89 0.0006
mRNA ENO1 FIMM pan-cancer AAC -0.57 0.0006
Download CSV