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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA RAF1 FIMM pan-cancer AAC 0.32 0.06
mRNA C1QB GDSC1000 pan-cancer AAC -0.067 0.06
mRNA GPR139 GDSC1000 pan-cancer AAC -0.066 0.06
mRNA C2orf78 GDSC1000 pan-cancer AAC 0.066 0.06
mRNA CCL8 FIMM pan-cancer AAC -0.31 0.06
mRNA TMEM196 GDSC1000 pan-cancer AAC 0.067 0.06
mRNA CA3 FIMM pan-cancer AAC 0.33 0.06
mRNA FHOD3 GDSC1000 pan-cancer AAC 0.072 0.06
mRNA PGM5 GDSC1000 pan-cancer AAC 0.066 0.06
mRNA PVR GDSC1000 pan-cancer AAC 0.077 0.06
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