1. Home/
  2. Compounds/
  3. GDC-0449

GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA OTUD6B GDSC1000 pan-cancer AAC 0.074 0.05
mRNA L2HGDH GDSC1000 pan-cancer AAC 0.075 0.05
mRNA BHLHA15 GDSC1000 pan-cancer AAC -0.07 0.05
mRNA PRDM15 GDSC1000 pan-cancer AAC -0.077 0.05
mRNA CD79B FIMM pan-cancer AAC 0.35 0.05
mRNA TRIB2 GDSC1000 pan-cancer AAC -0.083 0.05
mRNA TADA2A FIMM pan-cancer AAC 0.4 0.05
mRNA GON4L GDSC1000 pan-cancer AAC -0.076 0.05
mRNA PAK4 GDSC1000 pan-cancer AAC -0.083 0.05
mRNA C1QTNF1 FIMM pan-cancer AAC -0.35 0.05
Download CSV