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Compounds/
KU-55933

KU-55933

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	KU-55933
PharmacoGx	KU-55933

External IDs

Database	Identifier
Smiles:	C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4
Inchikey:	XRKYMMUGXMWDAO-UHFFFAOYSA-N
Pubchem:	5278396

Annotated Targets

ATM, PRKDC

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to KU-55933

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TGOLN2	CTRPv2	pan-cancer	AAC	-0.14	0.0005
mRNA	SPOCK3	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	FAM19A4	CTRPv2	pan-cancer	AAC	0.12	0.0005
mRNA	NEK9	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	GSTZ1	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	SMARCA4	CTRPv2	pan-cancer	AAC	0.14	0.0004
mRNA	TMEM126B	CTRPv2	pan-cancer	AAC	-0.13	0.0004
mRNA	DPH1	CTRPv2	pan-cancer	AAC	-0.13	0.0004
mRNA	CADPS2	CTRPv2	pan-cancer	AAC	-0.13	0.0003
mRNA	TCEAL1	CTRPv2	pan-cancer	AAC	-0.13	0.0003

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