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Compounds/
KU-55933

KU-55933

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	KU-55933
PharmacoGx	KU-55933

External IDs

Database	Identifier
Smiles:	C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4
Inchikey:	XRKYMMUGXMWDAO-UHFFFAOYSA-N
Pubchem:	5278396

Annotated Targets

ATM, PRKDC

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to KU-55933

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GPR132	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	NSUN4	GDSC1000	pan-cancer	AAC	0.12	0.001
mRNA	LIMD2	CTRPv2	pan-cancer	AAC	0.16	0.001
mRNA	CCDC8	CTRPv2	pan-cancer	AAC	0.13	0.001
mRNA	CYP27C1	GDSC1000	pan-cancer	AAC	0.12	0.001
mRNA	TVP23B	CTRPv2	pan-cancer	AAC	-0.13	0.001
mRNA	CAD	CTRPv2	pan-cancer	AAC	0.13	0.001
mRNA	OR8B8	CTRPv2	pan-cancer	AAC	0.11	0.001
mRNA	TEX35	GDSC1000	pan-cancer	AAC	-0.11	0.001
mRNA	NUDT13	CTRPv2	pan-cancer	AAC	-0.12	0.001

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