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AZD7762

AZD7762

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	AZD7762
PharmacoGx	AZD7762

External IDs

Database	Identifier
Smiles:	C1CC(CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N
Inchikey:	IAYGCINLNONXHY-LBPRGKRZSA-N
Pubchem:	11152667

Annotated Targets

CHEK1, CHEK2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD7762

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRSS57	CTRPv2	pan-cancer	AAC	0.17	2e-07
mRNA	SEC11C	GDSC1000	pan-cancer	AAC	-0.18	2e-07
mRNA	ZNF552	CTRPv2	pan-cancer	AAC	-0.19	2e-07
mRNA	MBP	CTRPv2	pan-cancer	AAC	-0.19	2e-07
mRNA	RNF166	CTRPv2	pan-cancer	AAC	0.19	2e-07
mRNA	SUN2	CTRPv2	pan-cancer	AAC	0.17	4e-07
mRNA	OCSTAMP	GDSC1000	pan-cancer	AAC	0.16	4e-07
mRNA	MREG	CTRPv2	pan-cancer	AAC	-0.18	4e-07
mRNA	TIFAB	CTRPv2	pan-cancer	AAC	0.16	5e-07
mRNA	TMEM9B	CTRPv2	pan-cancer	AAC	-0.18	5e-07

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