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AZD7762

AZD7762

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	AZD7762
PharmacoGx	AZD7762

External IDs

Database	Identifier
Smiles:	C1CC(CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N
Inchikey:	IAYGCINLNONXHY-LBPRGKRZSA-N
Pubchem:	11152667

Annotated Targets

CHEK1, CHEK2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD7762

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	AVPI1	GDSC1000	pan-cancer	AAC	0.16	0.0001
mRNA	BET1L	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	TRMT112	GDSC1000	pan-cancer	AAC	-0.12	0.0001
mRNA	SNX20	GDSC1000	pan-cancer	AAC	0.15	0.0001
mRNA	VPS37C	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	PXK	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	FOSL2	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	MLIP	CTRPv2	pan-cancer	AAC	-0.12	0.0001
mRNA	C12orf66	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	PIFO	GDSC1000	pan-cancer	AAC	-0.12	0.0001

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