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AZD7762

AZD7762

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	AZD7762
PharmacoGx	AZD7762

External IDs

Database	Identifier
Smiles:	C1CC(CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N
Inchikey:	IAYGCINLNONXHY-LBPRGKRZSA-N
Pubchem:	11152667

Annotated Targets

CHEK1, CHEK2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD7762

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SPOPL	CTRPv2	pan-cancer	AAC	-0.098	0.004
mRNA	MYO1G	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	NFATC2IP	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	MRPL41	CTRPv2	pan-cancer	AAC	-0.098	0.004
mRNA	METAP1	GDSC1000	pan-cancer	AAC	0.098	0.004
mRNA	HCFC1	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	RP11-426L16.10	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	VPS11	CTRPv2	pan-cancer	AAC	-0.098	0.004
mRNA	RP11-5A19.5	CTRPv2	pan-cancer	AAC	-0.096	0.004
mRNA	ERICH3	GDSC1000	pan-cancer	AAC	-0.091	0.004

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