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Axitinib

Synonyms

SourcesNames Used
GDSC1000, FIMMAxitinib
CTRPv2axitinib
PharmacoGx Axitinib

External IDs

DatabaseIdentifier
Smiles: CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
Inchikey: RITAVMQDGBJQJZ-FMIVXFBMSA-N
Pubchem: 6450551

Annotated Targets

CSF1, FLT1, FLT4, KDR, PLK4, FLT3, KIT, PDGFRA, PDGFRB

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Axitinib


Feature TypeStandardized
Nominal ANOVA
mRNA ABCA3 CTRPv2 pan-cancer AAC 0.13 0.0003
mRNA ABCB10 CTRPv2 pan-cancer AAC 0.18 2e-07
mRNA ABCB10 GDSC1000 pan-cancer AAC 0.14 0.0003
mRNA ABCB7 CTRPv2 pan-cancer AAC 0.13 0.0005
mRNA ABCC8 CTRPv2 pan-cancer AAC 0.16 2e-06
mRNA ABHD18 CTRPv2 pan-cancer AAC 0.15 0.0003
mRNA ABL1 GDSC1000 pan-cancer AAC 0.19 5e-07
mRNA ABL1 CTRPv2 pan-cancer AAC 0.14 4e-05
mRNA AC006538.4 CTRPv2 pan-cancer AAC 0.19 4e-07
mRNA AC007906.1 CTRPv2 pan-cancer AAC 0.12 0.0006
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