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Axitinib

Synonyms

SourcesNames Used
GDSC1000, FIMMAxitinib
CTRPv2axitinib
PharmacoGx Axitinib

External IDs

DatabaseIdentifier
Smiles: CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
Inchikey: RITAVMQDGBJQJZ-FMIVXFBMSA-N
Pubchem: 6450551

Annotated Targets

CSF1, FLT1, FLT4, KDR, PLK4, FLT3, KIT, PDGFRA, PDGFRB

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Axitinib


Feature TypeStandardized
Nominal ANOVA
mRNA GRM2 CTRPv2 pan-cancer AAC 0.12 0.0005
mRNA ZNF516 CTRPv2 pan-cancer AAC 0.12 0.0005
mRNA IFT57 GDSC1000 pan-cancer AAC -0.12 0.0005
mRNA HECTD4 CTRPv2 pan-cancer AAC 0.13 0.0005
mRNA HLA-DRA GDSC1000 pan-cancer AAC -0.15 0.0005
mRNA CLSPN CTRPv2 pan-cancer AAC 0.12 0.0005
mRNA SUMO2 CTRPv2 pan-cancer AAC 0.12 0.0005
mRNA OR8B12 GDSC1000 pan-cancer AAC 0.12 0.0005
mRNA ICA1L CTRPv2 pan-cancer AAC 0.12 0.0005
mRNA SEC22A GDSC1000 pan-cancer AAC -0.13 0.0005
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