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Axitinib

Axitinib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Axitinib
CTRPv2	axitinib
PharmacoGx	Axitinib

External IDs

Database	Identifier
Smiles:	CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
Inchikey:	RITAVMQDGBJQJZ-FMIVXFBMSA-N
Pubchem:	6450551

Annotated Targets

CSF1, FLT1, FLT4, KDR, PLK4, FLT3, KIT, PDGFRA, PDGFRB

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Axitinib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MLLT10	CTRPv2	pan-cancer	AAC	0.23	1e-10
mRNA	GATA1	GDSC1000	pan-cancer	AAC	0.23	1e-10
mRNA	HNRNPA1	CTRPv2	pan-cancer	AAC	0.25	1e-10
mRNA	MYB	CTRPv2	pan-cancer	AAC	0.27	2e-10
mRNA	SLC6A19	GDSC1000	pan-cancer	AAC	0.24	2e-10
mRNA	WHSC1L1	CTRPv2	pan-cancer	AAC	0.22	2e-10
mRNA	ASH2L	CTRPv2	pan-cancer	AAC	0.23	2e-10
mRNA	BRD3	CTRPv2	pan-cancer	AAC	0.22	2e-10
mRNA	SEPT5	CTRPv2	pan-cancer	AAC	0.23	2e-10
mRNA	ST8SIA6	GDSC1000	pan-cancer	AAC	0.22	3e-10

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