Home/
Compounds/
Axitinib

Axitinib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Axitinib
CTRPv2	axitinib
PharmacoGx	Axitinib

External IDs

Database	Identifier
Smiles:	CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
Inchikey:	RITAVMQDGBJQJZ-FMIVXFBMSA-N
Pubchem:	6450551

Annotated Targets

CSF1, FLT1, FLT4, KDR, PLK4, FLT3, KIT, PDGFRA, PDGFRB

FDA Approval Status

Approved

Dataset Select

Download Data as CSV

Top molecular features associated with response to Axitinib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TAL1	GDSC1000	pan-cancer	AAC	0.19	1e-07
mRNA	GAB2	GDSC1000	pan-cancer	AAC	0.2	1e-07
mRNA	KDM5B	CTRPv2	pan-cancer	AAC	0.18	1e-07
mRNA	SPATA5	CTRPv2	pan-cancer	AAC	0.18	1e-07
mRNA	SOCS2	CTRPv2	pan-cancer	AAC	0.18	1e-07
mRNA	POU2AF1	CTRPv2	pan-cancer	AAC	-0.2	1e-07
mRNA	PDGFRB	GDSC1000	pan-cancer	AAC	0.21	1e-07
mRNA	ARHGAP19	CTRPv2	pan-cancer	AAC	0.22	1e-07
mRNA	HDAC2	CTRPv2	pan-cancer	AAC	0.18	1e-07
mRNA	MEOX2	CTRPv2	pan-cancer	AAC	0.18	1e-07

← Previous 1 2…192021…199 200 Next →