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Axitinib

Axitinib

Synonyms

Sources	Names Used
GDSC1000, FIMM	Axitinib
CTRPv2	axitinib
PharmacoGx	Axitinib

External IDs

Database	Identifier
Smiles:	CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
Inchikey:	RITAVMQDGBJQJZ-FMIVXFBMSA-N
Pubchem:	6450551

Annotated Targets

CSF1, FLT1, FLT4, KDR, PLK4, FLT3, KIT, PDGFRA, PDGFRB

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Axitinib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	LCP2	GDSC1000	pan-cancer	AAC	0.26	1e-07
mRNA	NPIPA1	CTRPv2	pan-cancer	AAC	0.19	1e-07
mRNA	ACTN1	GDSC1000	pan-cancer	AAC	0.24	1e-07
mRNA	SLC2A4	CTRPv2	pan-cancer	AAC	0.18	1e-07
mRNA	NISCH	CTRPv2	pan-cancer	AAC	0.19	1e-07
mRNA	MTO1	GDSC1000	pan-cancer	AAC	0.22	1e-07
mRNA	PHF13	CTRPv2	pan-cancer	AAC	0.18	1e-07
mRNA	SQLE	CTRPv2	pan-cancer	AAC	0.17	1e-07
mRNA	GSE1	CTRPv2	pan-cancer	AAC	0.19	1e-07
mRNA	SOX4	CTRPv2	pan-cancer	AAC	0.18	1e-07

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