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ABT-888

ABT-888

Synonyms

Sources	Names Used
GDSC1000	Veliparib
CTRPv2	veliparib
PharmacoGx	ABT-888

External IDs

Database	Identifier
Smiles:	CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N
Inchikey:	JNAHVYVRKWKWKQ-CYBMUJFWSA-N
Pubchem:	11960529

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to ABT-888

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CD3G	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	TMEM45B	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	CRYBA4	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	SF3B6	CTRPv2	pan-cancer	AAC	-0.12	0.0009
mRNA	THEMIS	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	GATSL2	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	SYT11	CTRPv2	pan-cancer	AAC	0.14	0.0009
mRNA	LGALS8	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	KCNK5	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	ZIC2	CTRPv2	pan-cancer	AAC	0.12	0.001

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