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ABT-888

ABT-888

Synonyms

Sources	Names Used
GDSC1000	Veliparib
CTRPv2	veliparib
PharmacoGx	ABT-888

External IDs

Database	Identifier
Smiles:	CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N
Inchikey:	JNAHVYVRKWKWKQ-CYBMUJFWSA-N
Pubchem:	11960529

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to ABT-888

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SEMA5B	CTRPv2	pan-cancer	AAC	0.08	0.04
mRNA	TMEM14A	CTRPv2	pan-cancer	AAC	-0.079	0.04
mRNA	REM2	CTRPv2	pan-cancer	AAC	0.077	0.04
mRNA	MAP1LC3A	CTRPv2	pan-cancer	AAC	0.08	0.04
mRNA	KCTD12	CTRPv2	pan-cancer	AAC	0.081	0.04
mRNA	KCNH3	CTRPv2	pan-cancer	AAC	0.077	0.04
mRNA	RGS3	CTRPv2	pan-cancer	AAC	-0.083	0.04
mRNA	PTGER4	CTRPv2	pan-cancer	AAC	0.077	0.04
mRNA	FAM210A	CTRPv2	pan-cancer	AAC	-0.083	0.04
mRNA	DLL3	CTRPv2	pan-cancer	AAC	0.076	0.04

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