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ABT-888

ABT-888

Synonyms

Sources	Names Used
GDSC1000	Veliparib
CTRPv2	veliparib
PharmacoGx	ABT-888

External IDs

Database	Identifier
Smiles:	CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N
Inchikey:	JNAHVYVRKWKWKQ-CYBMUJFWSA-N
Pubchem:	11960529

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to ABT-888

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	AMER3	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	CYP3A4	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	FAM117B	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	MTRNR2L6	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	LCT	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	AGO4	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	MRPL17	CTRPv2	pan-cancer	AAC	-0.15	0.0001
mRNA	PIP5K1B	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	CBLN4	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	RAB2A	CTRPv2	pan-cancer	AAC	0.15	0.0001

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