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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA BOLA3 CTRPv2 pan-cancer AAC -0.18 2e-07
mRNA RAG1 CTRPv2 pan-cancer AAC 0.18 2e-07
mRNA GRID2IP CTRPv2 pan-cancer AAC 0.18 2e-07
mRNA RBM15 CTRPv2 pan-cancer AAC 0.21 2e-07
mRNA ZBED4 CTRPv2 pan-cancer AAC 0.21 2e-07
mRNA TMED3 CTRPv2 pan-cancer AAC -0.19 2e-07
mRNA TRIM22 CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA EMC7 CTRPv2 pan-cancer AAC -0.19 2e-07
mRNA TMED9 CTRPv2 pan-cancer AAC -0.19 2e-07
mRNA CEP68 CTRPv2 pan-cancer AAC 0.2 2e-07
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