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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA ABCC8 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA TPMT CTRPv2 pan-cancer AAC -0.11 0.002
mRNA ZNF559-ZNF177 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA DOK5 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA ZKSCAN4 CTRPv2 pan-cancer AAC 0.12 0.002
mRNA LIPT2 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA CPSF7 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA MRPS36 CTRPv2 pan-cancer AAC -0.11 0.002
mRNA AC010287.1 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA CDK7 CTRPv2 pan-cancer AAC -0.11 0.002
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