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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA CYFIP2 CTRPv2 pan-cancer AAC 0.21 3e-07
mRNA UBTF CTRPv2 pan-cancer AAC 0.2 3e-07
mRNA DENND6A CTRPv2 pan-cancer AAC 0.18 3e-07
mRNA ZMYM3 CTRPv2 pan-cancer AAC 0.19 3e-07
mRNA NAB1 CTRPv2 pan-cancer AAC 0.18 3e-07
mRNA IPO9 CTRPv2 pan-cancer AAC 0.19 3e-07
mRNA POU2F1 CTRPv2 pan-cancer AAC 0.2 3e-07
mRNA CRMP1 CTRPv2 pan-cancer AAC 0.2 3e-07
mRNA ARL11 CTRPv2 pan-cancer AAC 0.2 3e-07
mRNA HPS4 CTRPv2 pan-cancer AAC 0.18 3e-07
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