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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA PLGLB1 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA PPFIA2 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA ESRP2 CTRPv2 pan-cancer AAC -0.14 0.002
mRNA AL592183.1 CTRPv2 pan-cancer AAC 0.12 0.002
mRNA NR2C2 CTRPv2 pan-cancer AAC 0.12 0.002
mRNA AL078584.1 CTRPv2 pan-cancer AAC 0.12 0.002
mRNA LILRB5 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA CEP78 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA RP11-195F19.29 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA ARL10 CTRPv2 pan-cancer AAC 0.12 0.002
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