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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA SHPRH CTRPv2 pan-cancer AAC 0.21 7e-08
mRNA GDF11 CTRPv2 pan-cancer AAC 0.2 7e-08
mRNA SALL2 CTRPv2 pan-cancer AAC 0.19 7e-08
mRNA ZNF236 CTRPv2 pan-cancer AAC 0.19 7e-08
mRNA ZCCHC7 CTRPv2 pan-cancer AAC 0.19 7e-08
mRNA CENPV CTRPv2 pan-cancer AAC 0.2 7e-08
mRNA PHF14 CTRPv2 pan-cancer AAC 0.19 8e-08
mRNA NUDT11 CTRPv2 pan-cancer AAC 0.21 8e-08
mRNA TMEM208 CTRPv2 pan-cancer AAC -0.18 8e-08
mRNA HECA CTRPv2 pan-cancer AAC 0.2 8e-08
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