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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA IBA57 CTRPv2 pan-cancer AAC 0.2 3e-08
mRNA SH2D4B CTRPv2 pan-cancer AAC 0.19 3e-08
mRNA ZNF184 CTRPv2 pan-cancer AAC 0.22 3e-08
mRNA CBX5 CTRPv2 pan-cancer AAC 0.2 3e-08
mRNA HECTD4 CTRPv2 pan-cancer AAC 0.2 3e-08
mRNA C20orf96 CTRPv2 pan-cancer AAC 0.2 3e-08
mRNA ELAVL1 CTRPv2 pan-cancer AAC 0.21 3e-08
mRNA RFX3 CTRPv2 pan-cancer AAC 0.19 3e-08
mRNA RFX7 CTRPv2 pan-cancer AAC 0.21 4e-08
mRNA STMN1 CTRPv2 pan-cancer AAC 0.2 4e-08
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