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AZD-2281

Synonyms

SourcesNames Used
GDSC1000, FIMMOlaparib
CTRPv2olaparib
PharmacoGx AZD-2281

External IDs

DatabaseIdentifier
Smiles: C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Inchikey: FDLYAMZZIXQODN-UHFFFAOYSA-N
Pubchem: 23725625

FDA Approval Status

Approved
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Top molecular features associated with response to AZD-2281


Feature TypeStandardized
Nominal ANOVA
mRNA CTC1 CTRPv2 pan-cancer AAC 0.23 7e-09
mRNA EZH2 CTRPv2 pan-cancer AAC 0.22 7e-09
mRNA PIDD1 CTRPv2 pan-cancer AAC 0.21 7e-09
mRNA NCKAP1L CTRPv2 pan-cancer AAC 0.29 7e-09
mRNA SEMA6C CTRPv2 pan-cancer AAC 0.2 9e-09
mRNA PBRM1 CTRPv2 pan-cancer AAC 0.22 1e-08
mRNA CD19 CTRPv2 pan-cancer AAC 0.21 1e-08
mRNA TTC24 CTRPv2 pan-cancer AAC 0.2 1e-08
mRNA ALMS1 CTRPv2 pan-cancer AAC 0.21 1e-08
mRNA WIF1 CTRPv2 pan-cancer AAC 0.19 1e-08
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