1. Home/
  2. Compounds/
  3. ABT-263

ABT-263

Synonyms

SourcesNames Used
GDSC1000, FIMMNavitoclax
CTRPv2navitoclax
PharmacoGx ABT-263

External IDs

DatabaseIdentifier
Smiles: CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)NC(CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C
Inchikey: JLYAXFNOILIKPP-KXQOOQHDSA-N
Pubchem: 24978538

Annotated Targets

BCL2, BCL2L2, BAD

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ABT-263


Feature TypeStandardized
Nominal ANOVA
mRNA ADGRL2 FIMM pan-cancer AAC -0.55 0.0002
mRNA STYXL1 FIMM pan-cancer AAC -0.49 0.0004
mRNA MRPL24 CTRPv2 pan-cancer AAC -0.24 3e-11
mRNA THEM4 CTRPv2 pan-cancer AAC -0.23 6e-09
mRNA GPATCH4 CTRPv2 pan-cancer AAC -0.21 4e-09
mRNA MTX1 CTRPv2 pan-cancer AAC -0.21 5e-09
mRNA RAB13 CTRPv2 pan-cancer AAC -0.21 6e-07
mRNA MRPL9 CTRPv2 pan-cancer AAC -0.21 8e-09
mRNA DAP3 CTRPv2 pan-cancer AAC -0.21 9e-09
mRNA MRPS21 CTRPv2 pan-cancer AAC -0.21 1e-08
Download CSV