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Camptothecin

Synonyms

SourcesNames Used
GDSC1000Camptothecin
PharmacoGx Camptothecin

External IDs

DatabaseIdentifier
Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Inchikey: VSJKWCGYPAHWDS-FQEVSTJZSA-N
Pubchem: 24360

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to Camptothecin


Feature TypeStandardized
Nominal ANOVA
mRNA RFXAP GDSC1000 pan-cancer AAC 0.13 0.001
mRNA MAL2 GDSC1000 pan-cancer AAC -0.16 0.001
mRNA AGO4 GDSC1000 pan-cancer AAC 0.11 0.001
mRNA CAPRIN2 GDSC1000 pan-cancer AAC 0.12 0.001
mRNA DBR1 GDSC1000 pan-cancer AAC 0.11 0.001
mRNA DNM1L GDSC1000 pan-cancer AAC 0.11 0.001
mRNA SMAD7 GDSC1000 pan-cancer AAC -0.11 0.001
mRNA MESDC2 GDSC1000 pan-cancer AAC -0.11 0.001
mRNA TOPORS GDSC1000 pan-cancer AAC 0.11 0.001
mRNA CASQ2 GDSC1000 pan-cancer AAC -0.11 0.001
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