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Camptothecin

Synonyms

SourcesNames Used
GDSC1000Camptothecin
PharmacoGx Camptothecin

External IDs

DatabaseIdentifier
Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Inchikey: VSJKWCGYPAHWDS-FQEVSTJZSA-N
Pubchem: 24360

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to Camptothecin


Feature TypeStandardized
Nominal ANOVA
mRNA SLFN11 GDSC1000 pan-cancer AAC 0.49 4e-45
mRNA DEPTOR GDSC1000 pan-cancer AAC -0.23 4e-12
mRNA HACE1 GDSC1000 pan-cancer AAC 0.21 7e-10
mRNA TCTA GDSC1000 pan-cancer AAC -0.21 7e-10
mRNA DDX50 GDSC1000 pan-cancer AAC 0.21 2e-09
mRNA SEPT6 GDSC1000 pan-cancer AAC 0.3 3e-09
mRNA STOML1 GDSC1000 pan-cancer AAC -0.2 3e-09
mRNA CRYAB GDSC1000 pan-cancer AAC -0.22 5e-09
mRNA HM13 GDSC1000 pan-cancer AAC -0.21 6e-09
mRNA CCT4 GDSC1000 pan-cancer AAC 0.19 1e-08
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