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Camptothecin

Synonyms

SourcesNames Used
GDSC1000Camptothecin
PharmacoGx Camptothecin

External IDs

DatabaseIdentifier
Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Inchikey: VSJKWCGYPAHWDS-FQEVSTJZSA-N
Pubchem: 24360

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to Camptothecin


Feature TypeStandardized
Nominal ANOVA
mRNA PHGDH GDSC1000 pan-cancer AAC 0.12 0.0004
mRNA PNISR GDSC1000 pan-cancer AAC 0.13 0.0004
mRNA AP4B1 GDSC1000 pan-cancer AAC 0.14 0.0004
mRNA GAS7 GDSC1000 pan-cancer AAC 0.16 0.0004
mRNA SPON1 GDSC1000 pan-cancer AAC -0.13 0.0004
mRNA TCN2 GDSC1000 pan-cancer AAC -0.12 0.0004
mRNA IMPDH2 GDSC1000 pan-cancer AAC 0.13 0.0004
mRNA SASH3 GDSC1000 pan-cancer AAC 0.19 0.0004
mRNA ARNTL2 GDSC1000 pan-cancer AAC 0.13 0.0004
mRNA SLFN12 GDSC1000 pan-cancer AAC 0.13 0.0004
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