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Camptothecin

Synonyms

SourcesNames Used
GDSC1000Camptothecin
PharmacoGx Camptothecin

External IDs

DatabaseIdentifier
Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Inchikey: VSJKWCGYPAHWDS-FQEVSTJZSA-N
Pubchem: 24360

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to Camptothecin


Feature TypeStandardized
Nominal ANOVA
mRNA PDXK GDSC1000 pan-cancer AAC -0.14 0.0002
mRNA MMS22L GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA GRK5 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA TRMT11 GDSC1000 pan-cancer AAC 0.12 0.0002
mRNA SEC31B GDSC1000 pan-cancer AAC 0.15 0.0002
mRNA GRAMD1A GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA BNC1 GDSC1000 pan-cancer AAC 0.15 0.0002
mRNA IL1B GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA PPM1L GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA CUL3 GDSC1000 pan-cancer AAC 0.12 0.0002
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