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Camptothecin

Synonyms

SourcesNames Used
GDSC1000Camptothecin
PharmacoGx Camptothecin

External IDs

DatabaseIdentifier
Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Inchikey: VSJKWCGYPAHWDS-FQEVSTJZSA-N
Pubchem: 24360

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to Camptothecin


Feature TypeStandardized
Nominal ANOVA
mRNA GEMIN4 GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA SLC35F5 GDSC1000 pan-cancer AAC -0.15 0.0001
mRNA WIPI1 GDSC1000 pan-cancer AAC -0.14 0.0001
mRNA LMNB1 GDSC1000 pan-cancer AAC 0.14 0.0001
mRNA PTPN2 GDSC1000 pan-cancer AAC 0.14 0.0001
mRNA NPLOC4 GDSC1000 pan-cancer AAC -0.13 0.0001
mRNA AEBP2 GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA RNF13 GDSC1000 pan-cancer AAC -0.13 0.0001
mRNA SREK1IP1 GDSC1000 pan-cancer AAC 0.14 0.0001
mRNA ETV2 GDSC1000 pan-cancer AAC -0.13 0.0001
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