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Camptothecin

Synonyms

SourcesNames Used
GDSC1000Camptothecin
PharmacoGx Camptothecin

External IDs

DatabaseIdentifier
Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Inchikey: VSJKWCGYPAHWDS-FQEVSTJZSA-N
Pubchem: 24360

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to Camptothecin


Feature TypeStandardized
Nominal ANOVA
mRNA SIRT1 GDSC1000 pan-cancer AAC 0.14 9e-05
mRNA SLC25A45 GDSC1000 pan-cancer AAC -0.14 9e-05
mRNA CD63 GDSC1000 pan-cancer AAC -0.17 9e-05
mRNA NUP43 GDSC1000 pan-cancer AAC 0.13 9e-05
mRNA ZUFSP GDSC1000 pan-cancer AAC 0.14 9e-05
mRNA SYVN1 GDSC1000 pan-cancer AAC -0.14 9e-05
mRNA HNRNPC GDSC1000 pan-cancer AAC 0.14 9e-05
mRNA MRPL19 GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA PPIH GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA EBPL GDSC1000 pan-cancer AAC 0.13 0.0001
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