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Camptothecin

Synonyms

SourcesNames Used
GDSC1000Camptothecin
PharmacoGx Camptothecin

External IDs

DatabaseIdentifier
Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Inchikey: VSJKWCGYPAHWDS-FQEVSTJZSA-N
Pubchem: 24360

Annotated Targets

TOP1

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to Camptothecin


Feature TypeStandardized
Nominal ANOVA
mRNA TCOF1 GDSC1000 pan-cancer AAC 0.093 0.006
mRNA LSMEM1 GDSC1000 pan-cancer AAC -0.091 0.006
mRNA POU6F1 GDSC1000 pan-cancer AAC 0.097 0.006
mRNA ADAM28 GDSC1000 pan-cancer AAC -0.097 0.006
mRNA SCNN1A GDSC1000 pan-cancer AAC -0.11 0.006
mRNA CHCHD4 GDSC1000 pan-cancer AAC 0.096 0.006
mRNA AKR1C3 GDSC1000 pan-cancer AAC -0.1 0.006
mRNA C1orf127 GDSC1000 pan-cancer AAC -0.09 0.006
mRNA MRPL34 GDSC1000 pan-cancer AAC -0.1 0.006
mRNA ARHGEF37 GDSC1000 pan-cancer AAC -0.097 0.006
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