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Camptothecin

Synonyms

SourcesNames Used
GDSC1000Camptothecin
PharmacoGx Camptothecin

External IDs

DatabaseIdentifier
Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Inchikey: VSJKWCGYPAHWDS-FQEVSTJZSA-N
Pubchem: 24360

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to Camptothecin


Feature TypeStandardized
Nominal ANOVA
mRNA YEATS2 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA RHOH GDSC1000 pan-cancer AAC 0.16 0.003
mRNA TPMT GDSC1000 pan-cancer AAC -0.11 0.003
mRNA CHPF2 GDSC1000 pan-cancer AAC -0.1 0.003
mRNA MAN1A2 GDSC1000 pan-cancer AAC -0.1 0.003
mRNA PLBD2 GDSC1000 pan-cancer AAC -0.1 0.003
mRNA KIAA1522 GDSC1000 pan-cancer AAC -0.14 0.003
mRNA FAM167B GDSC1000 pan-cancer AAC -0.12 0.003
mRNA MARCH5 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA PIP5K1B GDSC1000 pan-cancer AAC -0.12 0.003
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