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Camptothecin

Synonyms

SourcesNames Used
GDSC1000Camptothecin
PharmacoGx Camptothecin

External IDs

DatabaseIdentifier
Smiles: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
Inchikey: VSJKWCGYPAHWDS-FQEVSTJZSA-N
Pubchem: 24360

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to Camptothecin


Feature TypeStandardized
Nominal ANOVA
mRNA POLR1D GDSC1000 pan-cancer AAC 0.1 0.007
mRNA HTR2A GDSC1000 pan-cancer AAC -0.09 0.007
mRNA SMIM5 GDSC1000 pan-cancer AAC -0.094 0.007
mRNA TSPAN10 GDSC1000 pan-cancer AAC -0.1 0.007
mRNA PARPBP GDSC1000 pan-cancer AAC 0.097 0.007
mRNA IL31RA GDSC1000 pan-cancer AAC 0.091 0.007
mRNA C16orf54 GDSC1000 pan-cancer AAC 0.12 0.007
mRNA RNF169 GDSC1000 pan-cancer AAC 0.092 0.007
mRNA SPATA7 GDSC1000 pan-cancer AAC 0.09 0.007
mRNA POLR2M GDSC1000 pan-cancer AAC 0.092 0.007
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