Summary Statistics

Cell Line DatasetAAC (%)IC50 (µM)EC50 (µM)Einf (%)DSS1 (arb.)
600MPE GRAY 31.499 1.2 1.18 0.865 0.279
AU565 GRAY 18.772 3.33 2.85 23.370 0.175
BT-549 GRAY 12.077 7.03 3.8 45.760 0.104
CAMA-1 GRAY 19.129 4.95 4.77 6.652 0.183
HCC1419 GRAY 4.356 N/A 4.23 79.670 0.0216
HCC1428 GRAY 22.721 3.57 3.55 0.454 0.21
HCC1954 GRAY 12.790 13.6 13.6 0.000 0.11
HCC2185 GRAY 14.909 7.06 4.14 31.022 0.128
Hs-578-T GRAY 8.558 N/A 4.42 59.409 0.0668
MCF10A GRAY 20.466 4.5 4.37 3.360 0.192
MDA-MB-134-VI GRAY 13.581 11.9 11.9 0.000 0.12
MDA-MB-175-VII GRAY 19.520 4.73 4.58 6.192 0.187
MDA-MB-231 GRAY 19.446 4.62 4.35 8.322 0.184
MDA-MB-361 GRAY 8.337 23.2 23.2 0.000 0.0738
MDA-MB-415 GRAY 19.085 5.09 4.94 5.601 0.183
BT-20 GRAY 8.756 N/A 7.96 58.450 0.0689
BT-474 GRAY 18.136 11.3 11.2 1.657 0.174
BT-483 GRAY 21.300 7.47 7.38 1.653 0.202
CAMA-1 GRAY 20.887 7.56 7.39 3.515 0.2
HCC1187 GRAY 28.003 3.29 3.29 0.000 0.258
HCC1187 GRAY 15.192 8.74 6.78 31.935 0.138
HCC1428 GRAY 23.082 6.21 6.21 0.000 0.211
HCC1806 GRAY 12.880 10.5 6.2 44.014 0.112
HCC2185 GRAY 14.338 9.3 6.81 35.663 0.129
HCC3153 GRAY 19.155 9.6 9.26 3.785 0.178
HCC38 GRAY 12.148 12.6 7.71 43.006 0.106
Hs-578-T GRAY 14.383 13.8 12.2 18.881 0.134
Hs-578-T GRAY 13.736 11.4 8.84 32.196 0.124
LY2 GRAY 33.189 1.38 1.3 5.490 0.316
MCF10A GRAY 24.337 4.46 2.7 18.170 0.209
MCF7 GRAY 24.780 2.62 0.975 33.750 0.212
MDA-MB-175-VII GRAY 21.215 7.1 6.95 4.087 0.204
MDA-MB-231 GRAY 16.348 12.4 11.8 9.275 0.155
MDA-MB-361 GRAY 21.030 7.48 7.37 2.961 0.203
MDA-MB-415 GRAY 20.500 7.93 7.76 3.610 0.196
MDA-MB-453 GRAY 16.796 11.5 10.9 9.768 0.159
MX-1 GRAY 21.590 7.32 7.27 0.866 0.204
SK-BR-3 GRAY 9.831 N/A 8.11 53.016 0.0807
SUM 1315M02 GRAY 20.536 8.02 7.88 2.901 0.197
SUM 1315M02 GRAY 12.255 12.1 6.49 45.909 0.105
SUM185PE GRAY 20.852 7.83 7.73 2.084 0.2
SUM225CWN GRAY 16.890 12 11.6 6.987 0.161
SUM 229PE GRAY 37.677 0.904 0.861 2.039 0.344
SUM 52PE GRAY 20.976 7.54 7.21 4.053 0.194
T47D GRAY 20.465 7.83 7.65 4.266 0.196
T47D_KBluc GRAY 21.117 7.49 7.38 2.517 0.203
BT-20 GRAY 12.608 38.1 38.1 0.000 0.0952
HCC1187 GRAY 7.728 N/A 1.53 77.715 0.044
HCC1428 GRAY 26.421 3.68 3.34 7.729 0.246
HCC2185 GRAY 3.789 N/A 2.23 88.066 0.00568
HCC38 GRAY 4.447 N/A 0.562 89.526 0.00134
Hs-578-T GRAY 0.436 188 188 0.000 0
BT-483 GRAY 19.712 N/A 0.274 58.979 0.161
600MPE GRAY 19.318 N/A 0.407 57.037 0.159
CAMA-1 GRAY 6.042 1.97e+05 1.97e+05 0.000 0
HBL-100 GRAY 12.172 34.4 34.4 0.000 0.0963
HCC1428 GRAY 18.002 3.94 1.38 49.239 0.155
HCC1569 GRAY 15.394 26.6 26.6 0.000 0.119
HCC1954 GRAY 3.994 N/A 1e+06 81.121 0
HCC2185 GRAY 7.114 N/A 1.38 79.950 0.0366
MCF10A GRAY 20.215 N/A 0.429 54.633 0.158
MCF10F GRAY 36.525 0.632 0.528 14.963 0.345
MCF12A GRAY 30.282 2.65 2.43 3.562 0.269
MDA-MB-134-VI GRAY 10.357 N/A 1e+06 55.465 0
MDA-MB-175-VII GRAY 11.881 124 124 0.000 0.0712
MDA-MB-231 GRAY 18.050 N/A 1.18 50.850 0.154
MDA-MB-361 GRAY 1.255 N/A 1.31 96.504 0
MDA-MB-415 GRAY 13.758 907 907 0.000 0
MDA-MB-361 GRAY 11.495 N/A 0.306 75.635 0.0717
SUM 1315M02 GRAY 18.321 N/A 0.254 62.323 0.145
SUM 229PE GRAY 32.421 0.438 0.35 29.751 0.303
SUM 52PE GRAY 31.714 0.397 0.304 32.861 0.294
184A1 GRAY 33.472 1.58 1.31 7.209 0.299
184B5 GRAY 31.536 1.06 0.538 26.351 0.28
184B5 GRAY 24.103 6.62 6.62 0.000 0.207
600MPE GRAY 29.552 3.18 3.18 0.000 0.26
AU565 GRAY 28.750 3.12 3.04 2.041 0.271
BT-20 GRAY 17.481 11.3 10.7 10.840 0.166
BT-474 GRAY 6.540 58.1 58.1 0.000 0.0576
BT-474 GRAY 20.169 9.45 9.34 2.252 0.194
BT-483 GRAY 21.153 8.39 8.28 1.943 0.201
BT-549 GRAY 22.438 6.83 6.7 3.344 0.216
CAMA-1 GRAY 5.146 69.8 69.8 0.000 0.0446
HCC1143 GRAY 28.380 3.53 3.53 0.000 0.256
HCC1187 GRAY 28.181 3.6 3.6 0.000 0.256
HCC1395 GRAY 13.357 11.5 7.78 39.438 0.118
HCC1395 GRAY 21.610 7.8 7.67 2.478 0.206
HCC1419 GRAY 18.272 11.6 11.2 4.908 0.173
HCC1419 GRAY 12.687 13.4 9.23 38.773 0.112
HCC1419 GRAY 9.160 42.7 42.7 0.000 0.0785
HCC1428 GRAY 26.183 5.97 5.97 0.000 0.216
HCC1569 GRAY 22.268 6.54 6.34 5.787 0.214
HCC1806 GRAY 26.657 N/A 0.0763 54.021 0.227
HCC1806 GRAY 17.364 7.94 6.65 25.373 0.161
HCC1937 GRAY 16.921 12.6 11.9 9.679 0.16
HCC1954 GRAY 21.270 8.18 8.09 2.181 0.205
HCC202 GRAY 11.179 18.2 8.54 47.575 0.095
HCC202 GRAY 6.952 54.9 54.9 0.000 0.062
HCC3153 GRAY 21.112 7.57 7.25 6.578 0.201
HCC38 GRAY 20.185 9.34 9.21 2.663 0.194
HCC70 GRAY 20.638 8.85 8.75 2.377 0.199
Hs-578-T GRAY 22.550 6.21 6.01 6.269 0.217
Hs-578-T GRAY 2.951 96.8 96.5 0.625 0.023
LY2 GRAY 36.152 1.16 1.07 3.690 0.331
LY2 GRAY 10.227 32.2 30.2 11.216 0.0941
MB 157 GRAY 28.258 5.46 5.46 0.000 0.227
MCF10A GRAY 26.849 4.29 4.29 0.000 0.243
MCF12A GRAY 26.497 3.31 1.61 23.098 0.227
MCF7 GRAY 29.847 2.99 2.99 0.000 0.266
MCF7 GRAY 31.743 2.13 2.02 2.744 0.289
MDA-MB-157 GRAY 29.262 319 319 0.000 0
MDA-MB-157 GRAY 18.413 10.2 9.69 9.484 0.175
MDA-MB-175-VII GRAY 5.985 63.4 63.4 0.000 0.0512
MDA-MB-231 GRAY 24.802 4.38 4.2 7.562 0.239
MDA-MB-361 GRAY 7.583 50.6 50.6 0.000 0.0679
MDA-MB-361 GRAY 11.787 15.1 7.85 46.375 0.101
MDA-MB-415 GRAY 14.342 30.2 30.2 0.000 0.11
MDA-MB-415 GRAY 25.180 5.42 5.42 0.000 0.224
MDA-MB-453 GRAY 8.414 48.3 48.3 0.000 0.0701
MDA-MB-453 GRAY 19.574 8.48 7.96 10.519 0.186
MX-1 GRAY 20.816 8.59 8.47 2.686 0.2
SK-BR-3 GRAY 21.086 8.21 8.05 3.194 0.202
SUM 1315M02 GRAY 21.205 8.25 8.14 2.287 0.203
SUM 1315M02 GRAY 8.282 46.4 46.4 0.000 0.0737
SUM 149PT GRAY 24.541 5.78 5.78 0.000 0.221
SUM 159PT GRAY 29.698 2.67 2.63 2.519 0.289
SUM185PE GRAY 22.528 7.33 7.33 0.000 0.21
SUM225CWN GRAY 26.108 4.03 3.93 4.560 0.253
SUM225CWN GRAY 5.446 67.4 67.4 0.000 0.047
SUM 229PE GRAY 37.593 0.981 0.935 2.481 0.349
SUM 52PE GRAY 27.569 3.68 3.54 2.354 0.253
T47D GRAY 7.775 50.2 50.2 0.000 0.0676
T47D_KBluc GRAY 8.722 44.2 44.2 0.000 0.0768
ZR-75-1 GRAY 20.724 8.71 8.58 2.649 0.199
ZR-75-30 GRAY 23.375 4.47 4.14 13.284 0.223
ZR75B GRAY 19.417 10.2 9.97 3.518 0.186
AU565 GRAY 22.126 3.67 3.6 2.454 0.21
BT-20 GRAY 17.641 6.29 5.66 8.261 0.159
BT-549 GRAY 18.863 5.73 5.7 1.303 0.181
HCC1187 GRAY 24.302 3.02 3.02 0.000 0.217
HCC1419 GRAY 17.319 5.66 5.28 12.076 0.164
HCC1428 GRAY 22.367 3.69 3.67 0.743 0.211
HCC1954 GRAY 10.141 N/A 0.000184 89.688 0.00315
HCC1954 GRAY 5.877 31.7 31.7 0.000 0.0519
HCC202 GRAY 5.951 31.4 31.4 0.000 0.0526
HCC2185 GRAY 16.226 6.25 5.52 16.167 0.15
HCC3153 GRAY 7.973 34.8 34.8 0.000 0.0568
HCC3153 GRAY 10.902 N/A 0.484 71.504 0.0746
Hs-578-T GRAY 7.632 N/A 1e+06 74.686 0
Hs-578-T GRAY 14.002 7.15 6 25.144 0.128
Hs-578-T GRAY 19.472 7.24 7.24 0.000 0.156
LY2 GRAY 22.262 0.673 0.389 44.293 0.197
MCF10A GRAY 34.867 0.709 0.662 3.014 0.317
MCF10F GRAY 24.149 0.619 0.252 44.266 0.211
MDA-MB-157 GRAY 9.879 20.3 20.3 0.000 0.0824
MDA-MB-231 GRAY 25.361 2.55 2.51 1.046 0.23
MDA-MB-453 GRAY 4.966 N/A 0.000107 90.067 0
MDA-MB-453 GRAY 6.732 28.4 28.4 0.000 0.0598
SK-BR-3 GRAY 19.128 5.03 4.81 6.379 0.181
SUM 1315M02 GRAY 12.968 N/A 0.135 73.133 0.0654
SUM 229PE GRAY 29.241 1.33 1.2 6.416 0.27
SUM 52PE GRAY 10.378 N/A 2.22 61.677 0.0617
T47D GRAY 9.505 20.2 20.2 0.000 0.0827
T47D_KBluc GRAY 0.808 125 125 0.000 0
T47D_KBluc GRAY 2.896 N/A 0.00896 94.218 0
UACC-812 GRAY 12.459 N/A 1e+06 69.296 0
184A1 GRAY 23.782 0.758 0.335 42.157 0.208
184A1 GRAY 26.768 0.562 0.309 35.895 0.24
184B5 GRAY 29.513 1.36 0.79 15.554 0.251
600MPE GRAY 30.774 1.56 1.56 0.000 0.259
AU565 GRAY 23.979 2.88 2.81 2.537 0.227
AU565 GRAY 27.944 1.71 1.67 2.443 0.265
BT-20 GRAY 0.228 N/A 89.9 55.632 0
BT-20 GRAY 5.482 N/A 9.62 64.820 0.0296
BT-474 GRAY 1.995 N/A 13.5 84.864 0.00175
BT-483 GRAY 20.420 4.53 4.43 3.053 0.194
BT-549 GRAY 18.720 5.66 5.53 3.211 0.177
BT-549 GRAY 18.182 6.29 6.26 1.072 0.175
CAMA-1 GRAY 2.879 8.39e+05 8.39e+05 0.000 0
CAMA-1 GRAY 18.458 5.46 5.28 6.340 0.176
HCC1143 GRAY 15.211 4.02 2.8 38.251 0.136
HCC1187 GRAY 20.240 4.78 4.68 1.959 0.189
HCC1187 GRAY 21.809 3.83 3.76 2.350 0.207
HCC1187 GRAY 20.359 5.07 5.07 0.000 0.18
HCC1395 GRAY 17.919 6.23 6.06 3.808 0.169
HCC1419 GRAY 6.084 30.9 30.9 0.000 0.0535
HCC1419 GRAY 9.711 16.6 15.1 15.809 0.0885
HCC1419 GRAY 17.742 6.26 6.12 4.387 0.17
HCC1428 GRAY 25.444 1.78 1.4 15.252 0.232
HCC1428 GRAY 22.119 3.78 3.73 1.331 0.207
HCC1428 GRAY 13.920 5.59 4.08 35.861 0.125
HCC1569 GRAY 7.495 N/A 2.54 70.476 0.051
HCC1569 GRAY 15.994 6.82 6.35 12.419 0.151
HCC1806 GRAY 3.601 2.74e+03 2.74e+03 0.000 0
HCC1937 GRAY 15.986 7.48 7.17 7.704 0.152
HCC1937 GRAY 1.974 N/A 2.73 92.047 0
HCC1954 GRAY 10.544 16.6 16.2 4.053 0.098
HCC1954 GRAY 13.237 11.9 11.3 5.063 0.117
HCC1954 GRAY 14.161 10.9 10.8 1.006 0.126
HCC1954 GRAY 19.808 4.92 4.85 2.724 0.191
HCC202 GRAY 10.537 16.1 15.5 7.158 0.0971
HCC202 GRAY 10.869 16 15.8 3.030 0.101
HCC2185 GRAY 13.776 8.6 6.73 22.748 0.123
HCC2185 GRAY 12.541 13.9 6.74 30.697 0.101
HCC2185 GRAY 18.672 4.2 3.82 15.966 0.176
HCC3153 GRAY 14.436 11 11 0.000 0.125
HCC3153 GRAY 15.247 12.7 12.7 0.000 0.12
HCC3153 GRAY 10.458 N/A 1.47 64.853 0.0665
HCC38 GRAY 15.639 8.48 8.32 3.264 0.148
HCC70 GRAY 18.829 5.62 5.55 2.516 0.181
Hs-578-T GRAY 7.731 N/A 4.42 63.328 0.0578
Hs-578-T GRAY 16.147 7 6.62 10.021 0.153
Hs-578-T GRAY 12.045 11.5 10.4 16.614 0.111
Hs-578-T GRAY 19.746 4.7 4.58 5.093 0.189
Hs-578-T GRAY 14.025 7.36 6.27 23.621 0.129
LY2 GRAY 24.061 2.64 2.57 4.834 0.232
LY2 GRAY 14.551 13.4 13.4 0.000 0.115
MB 157 GRAY 16.387 10.1 10.1 0.000 0.132
MCF10A GRAY 13.495 N/A 1.22 56.622 0.102
MCF10A GRAY 21.934 4.59 4.59 0.000 0.185
MCF10A GRAY 36.813 0.516 0.472 4.406 0.339
MCF10F GRAY 27.897 1.54 1.32 8.594 0.254
MCF7 GRAY 16.926 N/A 0.738 51.623 0.141
MCF7 GRAY 27.614 2.03 2.03 0.000 0.243
MDA-MB-134-VI GRAY 13.877 11.6 11.6 0.000 0.121
MDA-MB-157 GRAY 13.861 5.72 4.2 35.477 0.124
MDA-MB-157 GRAY 12.547 16.9 16.9 0.000 0.0986
MDA-MB-157 GRAY 10.603 19.2 19.2 0.000 0.0868
MDA-MB-175-VII GRAY 3.320 N/A 9.24 78.389 0.0154
MDA-MB-175-VII GRAY 17.495 6.38 6.21 5.103 0.167
MDA-MB-231 GRAY 16.433 6.83 6.5 9.162 0.156
MDA-MB-231 GRAY 17.930 5.71 5.39 8.265 0.169
MDA-MB-231 GRAY 17.762 3.9 3.32 23.777 0.165
MDA-MB-361 GRAY 2.586 9.92e+03 9.92e+03 0.000 0
MDA-MB-361 GRAY 8.796 21.9 21.9 0.000 0.0779
MDA-MB-415 GRAY 10.634 N/A 4.96 62.393 0.0399
MDA-MB-415 GRAY 17.381 6.37 6.16 6.040 0.166
MDA-MB-415 GRAY 21.482 3.84 3.74 4.003 0.205
MDA-MB-453 GRAY 12.415 6.49 3.51 45.710 0.107
MDA-MB-453 GRAY 18.218 5.02 4.7 11.582 0.173
MDA-MB-453 GRAY 19.422 4.33 4.08 10.485 0.185
MDA-MB-453 GRAY 16.420 6.03 5.5 15.262 0.154
MX-1 GRAY 19.140 5.25 5.14 3.895 0.183
SK-BR-3 GRAY 3.117 792 792 0.000 0
SK-BR-3 GRAY 20.763 4.34 4.25 2.942 0.197
SUM 1315M02 GRAY 13.275 5.34 3.12 44.198 0.115
SUM 1315M02 GRAY 8.323 N/A 0.344 79.797 0.0289
SUM 159PT GRAY 22.395 2.96 2.82 8.875 0.215
SUM185PE GRAY 20.739 4.36 4.29 2.716 0.198
SUM225CWN GRAY 18.237 5.19 4.87 10.294 0.173
SUM225CWN GRAY 9.976 17.5 17 6.296 0.0922
SUM 229PE GRAY 35.353 0.721 0.721 0.000 0.321
SUM 229PE GRAY 26.824 2.16 2.16 0.000 0.242
SUM 52PE GRAY 25.650 2.61 2.61 0.000 0.225
SUM 52PE GRAY 25.816 2.55 2.55 0.000 0.227
T47D GRAY 12.324 6.71 4.04 43.422 0.107
T47D GRAY 12.311 14.6 14.6 0.000 0.105
T47D_KBluc GRAY 13.524 5.31 3.43 41.340 0.119
T47D_KBluc GRAY 9.408 20.3 20.3 0.000 0.0826
T47D_KBluc GRAY 10.819 17.5 17.5 0.000 0.0922
UACC-812 GRAY 13.207 14 14 0.000 0.109
ZR-75-1 GRAY 13.784 N/A 0.635 64.370 0.0671
ZR-75-1 GRAY 11.036 2.91e+05 2.91e+05 0.000 0
ZR-75-30 GRAY 19.080 3.7 2.29 27.217 0.168
ZR75B GRAY 11.242 17.1 17.1 0.000 0.0943
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