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Cetuximab

Cetuximab

Synonyms

Sources	Names Used
GDSC1000	Cetuximab
PharmacoGx	Cetuximab

External IDs

Database	Identifier
Pubchem:	85668777

Annotated Targets

EGFR, FCGR3B, C1R, C1QA, C1QB, C1QC, FCGR3A, C1S, FCGR1A, FCGR2A, FCGR2B

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Cetuximab

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KLK7	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	FADS3	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	PODXL2	GDSC1000	pan-cancer	AAC	-0.11	0.002
mRNA	MGAT4B	GDSC1000	pan-cancer	AAC	0.12	0.002
mRNA	PKNOX1	GDSC1000	pan-cancer	AAC	-0.11	0.002
mRNA	WNT7B	GDSC1000	pan-cancer	AAC	0.12	0.002
mRNA	INTS6L	GDSC1000	pan-cancer	AAC	-0.13	0.002
mRNA	PLEKHB2	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	TMEM30A	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	NR1I2	GDSC1000	pan-cancer	AAC	0.12	0.002

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