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Cetuximab

Cetuximab

Synonyms

Sources	Names Used
GDSC1000	Cetuximab
PharmacoGx	Cetuximab

External IDs

Database	Identifier
Pubchem:	85668777

Annotated Targets

EGFR, FCGR3B, C1R, C1QA, C1QB, C1QC, FCGR3A, C1S, FCGR1A, FCGR2A, FCGR2B

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to Cetuximab

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SPRR1B	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	ZNF775	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	EGR1	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	RTN1	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	TAGLN3	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	TOP3A	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	DOHH	GDSC1000	pan-cancer	AAC	-0.12	0.0001
mRNA	STK17A	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	TCEAL2	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	ZC3H12A	GDSC1000	pan-cancer	AAC	0.13	0.0001

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