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XMD8-92

XMD8-92

Synonyms

Sources	Names Used
GDSC1000	XMD8-92
PharmacoGx	XMD8-92

External IDs

Database	Identifier
Smiles:	CCOc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCC(O)CC1
Pubchem:	46843772

Annotated Targets

DCLK2, MAPK7, PLK4, TNK1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XMD8-92

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FAM83F	GDSC1000	pan-cancer	AAC	-0.094	0.08
mRNA	MRPL41	GDSC1000	pan-cancer	AAC	-0.083	0.08
mRNA	TMEM245	GDSC1000	pan-cancer	AAC	0.086	0.08
mRNA	SLC18A1	GDSC1000	pan-cancer	AAC	-0.087	0.08
mRNA	STK11IP	GDSC1000	pan-cancer	AAC	0.085	0.08
mRNA	NEUROD6	GDSC1000	pan-cancer	AAC	-0.082	0.08
mRNA	POU6F2	GDSC1000	pan-cancer	AAC	-0.08	0.08
mRNA	HSD17B14	GDSC1000	pan-cancer	AAC	-0.082	0.08
mRNA	CCDC78	GDSC1000	pan-cancer	AAC	-0.087	0.08
mRNA	COL18A1	GDSC1000	pan-cancer	AAC	0.096	0.08

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