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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF77	GDSC1000	pan-cancer	AAC	0.12	0.0002
mRNA	ZNF771	GDSC1000	pan-cancer	AAC	0.079	0.01
mRNA	ZNF773	GDSC1000	pan-cancer	AAC	0.15	5e-06
mRNA	ZNF776	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	ZNF789	GDSC1000	pan-cancer	AAC	0.072	0.03
mRNA	ZNF790	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	ZNF813	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	ZNF814	GDSC1000	pan-cancer	AAC	0.11	0.0009
mRNA	ZNF829	GDSC1000	pan-cancer	AAC	0.099	0.001
mRNA	ZNF84	GDSC1000	pan-cancer	AAC	0.16	7e-07

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