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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	C16orf54	GDSC1000	pan-cancer	AAC	0.22	2e-08
mRNA	GAB3	GDSC1000	pan-cancer	AAC	0.22	4e-09
mRNA	LYL1	GDSC1000	pan-cancer	AAC	0.22	3e-07
mRNA	PRKCB	GDSC1000	pan-cancer	AAC	0.23	3e-08
mRNA	PPP1R27	GDSC1000	pan-cancer	AAC	0.23	4e-14
mRNA	NCKAP1L	GDSC1000	pan-cancer	AAC	0.23	7e-06
mRNA	RCSD1	GDSC1000	pan-cancer	AAC	0.23	5e-06
mRNA	DOCK8	GDSC1000	pan-cancer	AAC	0.23	5e-07
mRNA	MS4A6A	GDSC1000	pan-cancer	AAC	0.24	3e-14
mRNA	LCP2	GDSC1000	pan-cancer	AAC	0.24	2e-08

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