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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	BIN2	GDSC1000	pan-cancer	AAC	0.16	0.0002
mRNA	BORCS5	GDSC1000	pan-cancer	AAC	-0.12	0.0002
mRNA	OTULIN	GDSC1000	pan-cancer	AAC	-0.12	0.0002
mRNA	SETD1B	GDSC1000	pan-cancer	AAC	0.12	0.0002
mRNA	NLRP4	GDSC1000	pan-cancer	AAC	-0.12	0.0002
mRNA	SLA	GDSC1000	pan-cancer	AAC	0.14	0.0002
mRNA	ZNF879	GDSC1000	pan-cancer	AAC	0.12	0.0002
mRNA	ZNF227	GDSC1000	pan-cancer	AAC	0.12	0.0002
mRNA	CRYGD	GDSC1000	pan-cancer	AAC	0.12	0.0002
mRNA	WDR6	GDSC1000	pan-cancer	AAC	0.12	0.0002

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