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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MTMR8	GDSC1000	pan-cancer	AAC	0.14	4e-05
mRNA	TIMM13	GDSC1000	pan-cancer	AAC	0.13	4e-05
mRNA	TMEM217	GDSC1000	pan-cancer	AAC	0.13	4e-05
mRNA	ERG	GDSC1000	pan-cancer	AAC	0.13	4e-05
mRNA	SNX20	GDSC1000	pan-cancer	AAC	0.16	4e-05
mRNA	CD1A	GDSC1000	pan-cancer	AAC	0.13	4e-05
mRNA	INPP5D	GDSC1000	pan-cancer	AAC	0.2	5e-05
mRNA	GIMAP2	GDSC1000	pan-cancer	AAC	0.15	5e-05
mRNA	GGH	GDSC1000	pan-cancer	AAC	-0.13	5e-05
mRNA	RNASEH2B	GDSC1000	pan-cancer	AAC	0.16	5e-05

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