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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ADD1	GDSC1000	pan-cancer	AAC	0.14	1e-05
mRNA	ZNF268	GDSC1000	pan-cancer	AAC	0.13	2e-05
mRNA	RNF130	GDSC1000	pan-cancer	AAC	0.14	2e-05
mRNA	HLA-DQA1	GDSC1000	pan-cancer	AAC	-0.15	2e-05
mRNA	P2RY14	GDSC1000	pan-cancer	AAC	0.13	2e-05
mRNA	DUSP22	GDSC1000	pan-cancer	AAC	-0.15	2e-05
mRNA	PRKCQ	GDSC1000	pan-cancer	AAC	0.14	2e-05
mRNA	CD86	GDSC1000	pan-cancer	AAC	-0.16	2e-05
mRNA	COL23A1	GDSC1000	pan-cancer	AAC	0.13	2e-05
mRNA	PHF7	GDSC1000	pan-cancer	AAC	0.14	2e-05

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