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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RGMB	GDSC1000	pan-cancer	AAC	-0.072	0.03
mRNA	ABHD17C	GDSC1000	pan-cancer	AAC	-0.077	0.03
mRNA	HNRNPLL	GDSC1000	pan-cancer	AAC	0.07	0.03
mRNA	RCHY1	GDSC1000	pan-cancer	AAC	0.075	0.03
mRNA	TAB3	GDSC1000	pan-cancer	AAC	-0.068	0.03
mRNA	ACRV1	GDSC1000	pan-cancer	AAC	0.066	0.03
mRNA	USP31	GDSC1000	pan-cancer	AAC	0.075	0.03
mRNA	EBF3	GDSC1000	pan-cancer	AAC	0.071	0.03
mRNA	ZNF254	GDSC1000	pan-cancer	AAC	0.071	0.03
mRNA	EOMES	GDSC1000	pan-cancer	AAC	-0.067	0.03

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