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BIX02189

Synonyms

SourcesNames Used
GDSC1000BIX02189
PharmacoGx BIX02189

External IDs

DatabaseIdentifier
Smiles: CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem: 46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved
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Top molecular features associated with response to BIX02189


Feature TypeStandardized
Nominal ANOVA
mRNA CAST GDSC1000 pan-cancer AAC -0.15 2e-05
mRNA ZBTB16 GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA IRAK3 GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA NCKAP1 GDSC1000 pan-cancer AAC -0.25 2e-05
mRNA ZEB2 GDSC1000 pan-cancer AAC 0.16 2e-05
mRNA SLC25A4 GDSC1000 pan-cancer AAC -0.14 2e-05
mRNA CELF2 GDSC1000 pan-cancer AAC 0.18 2e-05
mRNA ZC2HC1A GDSC1000 pan-cancer AAC -0.14 2e-05
mRNA OCSTAMP GDSC1000 pan-cancer AAC 0.13 2e-05
mRNA PBRM1 GDSC1000 pan-cancer AAC 0.15 2e-05
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