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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NCKAP1L	GDSC1000	pan-cancer	AAC	0.23	7e-06
mRNA	EFCAB2	GDSC1000	pan-cancer	AAC	0.13	8e-06
mRNA	BRD3	GDSC1000	pan-cancer	AAC	0.14	9e-06
mRNA	LMO2	GDSC1000	pan-cancer	AAC	0.16	9e-06
mRNA	IL17RA	GDSC1000	pan-cancer	AAC	0.15	9e-06
mRNA	ITGAM	GDSC1000	pan-cancer	AAC	0.14	9e-06
mRNA	S1PR4	GDSC1000	pan-cancer	AAC	0.19	9e-06
mRNA	ZNF197	GDSC1000	pan-cancer	AAC	0.14	1e-05
mRNA	P2RX1	GDSC1000	pan-cancer	AAC	0.16	1e-05
mRNA	PRTN3	GDSC1000	pan-cancer	AAC	0.14	1e-05

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