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BIX02189

BIX02189

Synonyms

Sources	Names Used
GDSC1000	BIX02189
PharmacoGx	BIX02189

External IDs

Database	Identifier
Smiles:	CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem:	46931012

Annotated Targets

MAP2K5, MAPK7

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX02189

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PHLDA1	GDSC1000	pan-cancer	AAC	-0.086	0.03
mRNA	C1orf216	GDSC1000	pan-cancer	AAC	0.074	0.03
mRNA	JCHAIN	GDSC1000	pan-cancer	AAC	-0.083	0.03
mRNA	NLGN1	GDSC1000	pan-cancer	AAC	-0.075	0.03
mRNA	THAP1	GDSC1000	pan-cancer	AAC	0.072	0.03
mRNA	MLXIP	GDSC1000	pan-cancer	AAC	0.072	0.03
mRNA	PLAC8L1	GDSC1000	pan-cancer	AAC	0.071	0.03
mRNA	SRP72	GDSC1000	pan-cancer	AAC	0.072	0.03
mRNA	PKN3	GDSC1000	pan-cancer	AAC	0.069	0.03
mRNA	RFX8	GDSC1000	pan-cancer	AAC	0.073	0.03

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