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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA HEATR5A GDSC1000 pan-cancer AAC -0.17 2e-07
mRNA TDG GDSC1000 pan-cancer AAC 0.16 2e-07
mRNA ABCC4 GDSC1000 pan-cancer AAC -0.16 2e-07
mRNA AMER2 GDSC1000 pan-cancer AAC 0.17 2e-07
mRNA UBXN2B GDSC1000 pan-cancer AAC 0.15 2e-07
mRNA MEX3A GDSC1000 pan-cancer AAC 0.17 2e-07
mRNA RNF219 GDSC1000 pan-cancer AAC 0.16 2e-07
mRNA IL6ST GDSC1000 pan-cancer AAC -0.17 2e-07
mRNA RPAIN GDSC1000 pan-cancer AAC 0.16 2e-07
mRNA GNS GDSC1000 pan-cancer AAC -0.17 2e-07
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