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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA CYP4F11 GDSC1000 pan-cancer AAC -0.087 0.005
mRNA CORO1A GDSC1000 pan-cancer AAC 0.15 0.005
mRNA KIF1C GDSC1000 pan-cancer AAC -0.097 0.005
mRNA OR5M1 GDSC1000 pan-cancer AAC 0.084 0.005
mRNA MIB1 GDSC1000 pan-cancer AAC 0.084 0.005
mRNA TXNDC16 GDSC1000 pan-cancer AAC 0.088 0.005
mRNA BAMBI GDSC1000 pan-cancer AAC -0.093 0.005
mRNA CARS2 GDSC1000 pan-cancer AAC 0.081 0.005
mRNA GPR18 GDSC1000 pan-cancer AAC 0.11 0.005
mRNA FNDC8 GDSC1000 pan-cancer AAC 0.084 0.005
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